I was trying to integrate QAD 6.0 with a JIRA instance that was set up on a secure server outside of our firewall. I was told by Micro Focus that the current integration doesn't support SSL at this time.
So, if your JIRA instance is setup with an HTTPS:// address so that you can work globally it won't integrate at this time.
You also need to set up JIRA to allow third party integration. The server is the name of the server its self. The port we used was 80. Make sure you are using an active JIRA user. Without some modifications (probable quite a bit) when you create a defect from QAD it creates a new Bug item in JIRA. I researched this and since it would take more work (development and other) to make the solution work for us we have decided not to continue with this effort.