According to documentation IE 8.0 is not listed as a compatible browser. I would recommend the use of QCExplorer.
While I have been working for Businesses that are Vendor partners with HP, IBM and Microsoft, my opinions and advice is my own.
The solutions provided are either sourced from my own scripting libraries or from a quick Google Search.
The Quality Center Explorer Add-in enables you to use Quality Center without using a Web browser, such as Microsoft Internet Explorer. This is useful if you are unable to download ActiveX controls, or if your browser restricts the use of ActiveX components. The only components that are downloaded when you use Quality Center Explorer are Quality Center components
Use the add-ins link on the main QC page to access the HP page for all add-ins for your current level of QC. This will include a link to the QCExplorer.